You can't tell the story of southern hip-hop without mentioning the Three 6 Mafia. Founded by Juicy J, Lord Infamous, and DJ Paul, the Memphis group became hometown heroes with their pioneering crunk sound. Their indie label, Hypnotized Minds, also brought through local artists like Gangsta Boo and Project Pat. After serving the underground scene with a stream of menacing music throughout the '90s, the group finally cracked the mainstream with a triumphant Oscar winning contribution to the Hustle and Flow soundtrack in 2006.